Current Thinking on Malignant Salivary Gland Neoplasms
نویسندگان
چکیده
منابع مشابه
Review of Salivary Gland Neoplasms
Salivary gland tumours most often present as painless enlarging masses. Most are located in the parotid glands and most are benign. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours. Investigations such as fine needle aspiration cytology and MRI scans provide some useful information, but most cases will require surgical excision as a...
متن کاملMalignant salivary gland tumors
Salivary gland neoplasms are a heterogeneous and important group of tumors of the Oral and Maxillofacial Pathology. They comprise from 2 to 3% of all the salivary gland lesions and tumors1,2 because their heterogeneity, since several years, different classifications based in clinical or microscopic criteria had been appeared.3-7 The most recent and most widely used is that proposed by Seifert e...
متن کاملMalignant Salivary Gland Tumours
PCNA (proliferating cell nuclear antigen) immunoreactivity is high in malignancy. (Also ki67 antibodies) and thus provides a useful diagnostic tool. Ki67 has prognostic significance in Adenoid Cystic Carcinoma. Bcl 2 and apoptotic index are good prognostic markers. Bax is proapoptotic (in salivary neoplasms there is decreased Bcl 2 and increased Bax leading to increased apoptosis ) Cytokeratin ...
متن کاملMTA1 Expression in Benign and Malignant Salivary gland Tumors
Introduction: Salivary gland tumors (SGTs) are important parts of human neoplasms. The most common SGT is pleomorphic adenoma and the most common malignant SGTs are mucoepidermoid carcinoma and adenoid cystic carcinoma (ACC). Metastasis-associated genes 1 (MTA1), a member of the nucleosome remodeling and histone deacetylation complex, is one newly discovered gene which recruits histone deacetyl...
متن کاملNeoangiogenesis in Benign and Malignant Salivary Gland Tumors
Introduction: There are few studies investigating the role of neoangiogenesis in biological behavior of salivary gland tumors. CD105 expression has demonstrated greater accuracy for detecting new vessel formation compared with other pan-endothelial molecules. This study aimed to assess and compare intratumoral Micro-Vessel Density (MVD) through using immunohistochemichal expression of CD105 bio...
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ژورنال
عنوان ژورنال: Journal of Cancer Treatment and Research
سال: 2013
ISSN: 2376-7782
DOI: 10.11648/j.jctr.20130101.12